2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P10795
    NK-2
    		Inhibitor
    NK-2 (Antibiotic NK 2), a shortened linear amphipathic NK-Lysin analog (comprising residues 39 to 65 of NK-lysin), is an antimicrobial peptide that exhibits potent activities against trypanosoma cruzi, Candida albicans, gram-positive and gram-negative bacteria. NK-2 can kill trypanosomes residing inside the human glioblastoma cell line 86HG39, left the host cells apparently unharmed.
    NK-2
  • HY-119419R
    Pirimicarb (Standard)
    		Inhibitor
    Pirimicarb (Standard) is the analytical standard of Pirimicarb. This product is intended for research and analytical applications. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide.
    Pirimicarb (Standard)
  • HY-19054
    CGP-20376
    		Inhibitor
    CGP-20376, a 5-methoxyl-6-dithiocarbamic-S- (2-carboxy-ethyl) ester derivative of Benzothiazole (HY-W012634), is an orally active and potent antifilarial drug. CGP-20376 has anthelmintic activity.
    CGP-20376
  • HY-W008216S
    HMMNI-d3
    		Inhibitor
    HMMNI-d3 (Hydroxy Dimetridazole-d3) is deuterium labeled HMMNI (HY-W008216). HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class agent that combats protozoan infections.
    HMMNI-d<sub>3</sub>
  • HY-N0565BR
    Doxycycline hyclate (Standard)
    Doxycycline hyclate (Standard) is the analytical standard of Doxycycline hyclate. This product is intended for research and analytical applications. Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity.
    Doxycycline hyclate (Standard)
  • HY-N0402R
    Artemether (Standard)
    		Inhibitor
    Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria.
    Artemether (Standard)
  • HY-123652
    Etofamide
    Etofamide is an antimicrobial agent with IC50 value of 5.96 mg/L against amoeba.
    Etofamide
  • HY-146041
    Antiparasitic agent-2
    		Inhibitor
    Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM).
    Antiparasitic agent-2
  • HY-12785S1
    Albendazole sulfoxide-d7
    		Inhibitor
    Albendazole sulfoxide-d7 is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].
    Albendazole sulfoxide-d<sub>7</sub>
  • HY-B1064A
    Clindamycin phosphate hydrochloride
    		Inhibitor
    Clindamycin phosphate (Clindamycin 2-phosphate) hydrochloride is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate hydrochloride is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate hydrochloride can be used for researching acne and bacterial vaginosis.
    Clindamycin phosphate hydrochloride
  • HY-N10624
    Koshidacin B
    		Inhibitor
    Koshidacin B is an antiplasmodial cyclic tetrapeptide with antiplasmodial activity against P. falciparum FCR3 and K1 strain with IC50 values of 0.89 and 0.83 μM, respectively. Koshidacin B suppresses malaria parasites in vivo, it can be used for the research of parasites infection.
    Koshidacin B
  • HY-147766
    Antileishmanial agent-10
    		Inhibitor
    Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent.
    Antileishmanial agent-10
  • HY-155024
    HAT-IN-8
    		Inhibitor
    HAT-IN-8 (Compound 38) is a BBB-penetrable T. brucei inhibitor (EC50: 0.18 μM). HAT-IN-8 can be used for the research of Human African trypanosomiasis.
    HAT-IN-8
  • HY-17589S1
    Chloroquine-d4 phosphate
    		Inhibitor
    Chloroquine-d4 (phosphate) is the deuterium labeled Chloroquine phosphate. Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM)[1][2][3][4].
    Chloroquine-d<sub>4</sub> phosphate
  • HY-126601
    Malonganenone A
    		Inhibitor
    Malonganenone A is an antimalarial marine alkaloid that disrupts the interaction between PfHsp70-x and Hsp40. Malonganenone A inhibits plasmodial and not human Hsp70 ATPase activity (Hsp40-stimulated), and hindered the aggregation suppression activity of PfHsp70-x.
    Malonganenone A
  • HY-146744
    Antileishmanial agent-4
    		Inhibitor
    Antileishmanial agent-4 is a ribonucleoside analogue and acts as an antileishmanial agent.
    Antileishmanial agent-4
  • HY-163395
    3-Tosylimidazolidine-2,4-dione
    		Inhibitor
    3-Tosylimidazolidine-2,4-dione (compound 2C) is a hydantoins derivative, and exhibits inhibitory activity against the Pf3D7 strain, with an IC50 value of 3.97  nM.
    3-Tosylimidazolidine-2,4-dione
  • HY-126406
    Tirandamycin A
    		Inhibitor
    Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties.
    Tirandamycin A
  • HY-107212R
    Selamectin (Standard)
    		Inhibitor
    Selamectin (Standard) is the analytical standard of Selamectin. This product is intended for research and analytical applications. Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, Lymphatic filariae, and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC50 of 120 nM.
    Selamectin (Standard)
  • HY-B1194A
    Tetramisole
    		Inhibitor
    Tetramisole is an orally active, selective inward rectifier potassium channel agonist with an EC50 of approximately 30 μM for the Kir2.1 subunit. Tetramisole is also an anti-nematode agent that blocks neuromuscular transmission by non-competitive depolarization. Tetramisole promotes the forward transport of Kir2.1 channels, hyperpolarizes the resting potential (RP), shortens the action potential duration (APD), inhibits intracellular calcium overload and the PKA signaling pathway, and exerts anti-arrhythmic and anti-myocardial remodeling activities. Tetramisole can be used in cardiac electrophysiology research and research related to myocardial ischemia and heart failure.
    Tetramisole
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.